CollaFibR™ for cell and tissue culture
The 3D tissue culture market is an unregulated $1.6B market that is growing at 15-20% compound annual growth. The market is focused on the global research community that is looking for highly organized 3D tissue culture to better mimic the biology of complex tissues, to increase the efficiency of drug and vaccine development, and decrease our dependence on animal models. Directed at this market, we have developed 2 products, which together provide a comprehensive collagen based platform for cell and tissue growth in both 2D and 3D.
CollaFibR™ 2D cell culture plates
A CollaFibR™ 2D cell culture plate is a highly organized linear array of our collagen fibers laid on a gel, seeded into a traditional cell culture plate. As shown in the images, CollaFibR™ promotes excellent cell attachment, induces cellular alignment, and allows cells to manipulate the collagen environment.
CollaFibR™ 3D Scaffold
A CollaFibR™ scaffold for cell growth, composed of 200 layers of our collagen fibers, in a linear or cross-hatched geometry, as shown in the first two rows on the right. Seeded in a well plate, this product comes sterilized and ready to use for your 3D cell culture and tissue culture experiments. Compared to other 3D cell culture products such as Matrigel®, this product has superior batch-to-batch consistency, induces excellent cellular alignment, and has adequate thickness for cell migration. The last row on the right shows images of cells growing in 3D within these scaffolds.
A multifilament CollaFibR™ fiber is an excellent artificial tendon model. Composed of 30,000 filaments of 600 nm diameter, the CollaFibR™ tendon shows a tensile strength of 250 MPa – 3X higher than native human tendons. While using natural collagen sources, CollaFibR™ can serve as excellent artificial tendon in both tissue models and medical applications. Tendon prototypes are currently being tested by key opinion leaders.
A spider silk prototype with endless potential
Five times stronger than steel while more flexible than rubber, spider silk is one of nature’s most exquisite materials. With nearly endless applications from advanced sutures to ballistic protection, scientists have been trying to replicate spider silk for decades. Using spider silk proteins, the prototype SpidrFibR™ has excellent mechanical properties and shows excellent potential for applications in the green textile industry, and in bio-composite development for aerospace engineering and defence. The SpidrFibR™ prototypes show strength greater than steel and further work is ongoing.